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* [http://ldp.library.jhu.edu/projects/gamera Gamera Project] looks a very promising framework written in python ...

I think the easiest would be to use kooka or xsane, scan an image and do OCR or importing an existing image into kooka and do OCR.

A [http://www.wired.com/gadgets/miscellaneous/news/2007/06/iliad_scan robot scans Ancient Manuscript in 3-D]. Also, This summer a group of graduate and undergraduate students of Greek will gather at the [http://chs.harvard.edu/ Center for Hellenic Studies] in Washington, D.C., to produce XML transcriptions of the text. Eventually, their work will be posted online for anyone to search under [http://creativecommons.org/about/licenses/ Creative Commons] licence.